4-BENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
1-Benzyl-4-Boc-piperazine
CAS: 57260-70-5
Molecular Formula: C16H24N2O2
4-BENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Names and Identifiers
| Name | 1-Benzyl-4-Boc-piperazine |
| Synonyms | 1-Boc-4-Benzylpiperazine 1-Benzyl-4-Boc-piperazine 4-BENZYL-1-BOC-PIPERAZINE 1-Boc-(4-benzyl)piperazine 1-N-Boc-4-benzylpiperazine 4-BENZYL-1-T-BUTOXYCARBONYLPIPERAZINE 1-Benzyl-4-(tert-butoxycarbonyl)piperazine tert-butyl 4-benzylpiperazine-1-carboxylate 4-BENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-(phenylmethyl)-1-piperazinecarboxylic acid tert-butyl ester 1-Benzyl-4-(tert-butoxycarbonyl)piperazine~tert-Butyl 4-benzyl-1-piperazinecarboxylate |
| CAS | 57260-70-5 |
| InChI | InChI=1/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-17(10-12-18)13-14-7-5-4-6-8-14/h4-8H,9-13H2,1-3H3 |
4-BENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Physico-chemical Properties
| Molecular Formula | C16H24N2O2 |
| Molar Mass | 276.37 |
| Density | 1.087±0.06 g/cm3(Predicted) |
| Melting Point | 71-73°C(lit.) |
| Boling Point | 362.5±35.0 °C(Predicted) |
| Flash Point | 173.1°C |
| Vapor Presure | 1.92E-05mmHg at 25°C |
| BRN | 797033 |
| pKa | 6.50±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.538 |
| MDL | MFCD00075603 |
4-BENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
4-BENZYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Introduction
1-Benzyl-4-Boc-piperazine is an organic compound with the chemical formula C18H28N2O2.
Nature:
-Appearance: White crystalline solid
-Melting point: about 114-116 degrees Celsius
-Solubility: Soluble in common organic solvents such as chloroform, dichloromethane and dimethylformamide, almost insoluble in water.
Use:
- 1-Benzyl-4-Boc-piperazine is an intermediate compound, often used in organic synthesis to synthesize biologically active molecules, such as drugs and pesticides.
Preparation Method:
The preparation of 1-Benzyl-4-Boc-piperazine is generally accomplished by the following steps:
1.4-piperazinecarbonyl chloride is reacted with benzylamine to obtain 1-benzyl -4-piperazinecarboxamide.
2.1-benzyl -4-piperazine carboxamide is reacted with tert-butoxycarbonylating agent (such as tert-butyl chloroformate) to generate 1-Benzyl-4-Boc-piperazine.
Safety Information:
- 1-Benzyl-4-Boc-piperazine is not flammable at room temperature, but may produce toxic gases under open flames or high temperatures.
-Contact with skin may cause irritation. Wear appropriate protective gloves and clothing.
-Inhalation or ingestion may pose a risk to human health. Avoid inhaling dust or contact with the mouth and eyes.
-When using or storing, please pay attention to comply with the regulations for safe operation and disposal of waste, and keep away from ignition and oxidizing agents.
Nature:
-Appearance: White crystalline solid
-Melting point: about 114-116 degrees Celsius
-Solubility: Soluble in common organic solvents such as chloroform, dichloromethane and dimethylformamide, almost insoluble in water.
Use:
- 1-Benzyl-4-Boc-piperazine is an intermediate compound, often used in organic synthesis to synthesize biologically active molecules, such as drugs and pesticides.
Preparation Method:
The preparation of 1-Benzyl-4-Boc-piperazine is generally accomplished by the following steps:
1.4-piperazinecarbonyl chloride is reacted with benzylamine to obtain 1-benzyl -4-piperazinecarboxamide.
2.1-benzyl -4-piperazine carboxamide is reacted with tert-butoxycarbonylating agent (such as tert-butyl chloroformate) to generate 1-Benzyl-4-Boc-piperazine.
Safety Information:
- 1-Benzyl-4-Boc-piperazine is not flammable at room temperature, but may produce toxic gases under open flames or high temperatures.
-Contact with skin may cause irritation. Wear appropriate protective gloves and clothing.
-Inhalation or ingestion may pose a risk to human health. Avoid inhaling dust or contact with the mouth and eyes.
-When using or storing, please pay attention to comply with the regulations for safe operation and disposal of waste, and keep away from ignition and oxidizing agents.
Last Update：2024-04-09 15:17:58
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Product Name: 1-Benzyl-4-Boc-Piperazine Visit Supplier Webpage Request for quotation
CAS: 57260-70-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 57260-70-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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